Amastan / MSTN
نویسندگان
چکیده
منابع مشابه
The Mstn mutation impairs secretion of promyostatin
Hypermuscularity of Compact mouse is caused by a 12-bp deletion in the myostatin gene, but the molecular basis of decreased myostatin activity is unclear since the deletion does not affect the integrity of the growth factor domain. In the present work we show that the deletion causes misfolding and impaired secretion of myostatin precursor with concomitant decrease in myostatin activity. We sug...
متن کاملRabbit MSTN gene polymorphisms and genetic effect analysis.
We analyzed meat samples of nine pure lines of rabbit and its 37 hybrid combinations by sequencing and single-strand conformation polymorphism techniques to explore genetic polymorphisms of all the three exon regions and part of the 5'-regulatory region of the myostatin (MSTN) gene. Thus, we detected a single nucleotide mutation (T→C) on the 476 locus of the 5'-regulatory region, but no mutatio...
متن کاملRunning Head: MSTN gene SNP association with speed in racehorses
3 Emmeline W Hill, Rita G Fonseca, Beatrice A McGivney, Jingjing Gu, David E 4 MacHugh and Lisa M Katz 5 6 School of Agriculture and Food Science,, University College Dublin, Belfield, Dublin 4, 7 Ireland 8 9 School of Veterinary Medicine, University College Dublin, Belfield, Dublin 4, Ireland 10 11 * Corresponding author 12 13 Running Head: MSTN gene SNP association with speed in racehorses 14...
متن کاملFoxO1 is not a key transcription factor in the regulation of myostatin (mstn-1a and mstn-1b) gene expression in trout myotubes.
In mammals, much evidence has demonstrated the important role of myostatin (MSTN) in regulating muscle mass and identified the transcription factor forkhead box O (FoxO) 1 as a key regulator of its gene expression during atrophy. However, in trout, food deprivation leads to muscle atrophy without an increase of the expression of mstn genes in the muscle. We therefore studied the relationship be...
متن کاملEffect of MSTN propeptide protein on the growth and development of Altay lamb muscle.
Prokaryotic expression technology was used to express maltose-binding protein binding myostatin (MSTN) propeptide fusion protein. Six disease-free Altay lambs were used in this study. The right leg gastrocnemii were injected with MSTN recombinant propeptide protein. The left leg gastrocnemii (the control group) were injected with the same dose of phosphate based saline. The lambs were fed durin...
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ژورنال
عنوان ژورنال: Encyclopédie berbère
سال: 1986
ISSN: 1015-7344,2262-7197
DOI: 10.4000/encyclopedieberbere.2463